I have had MANY years of digestive issues, pain, bloating, etc. I finally got a doctor to quit saying you have CF and IBS…what do you want me to do? I ask the doctor to ignore the CF and pretend that I could have a problem other than CF. He ordered a barium enema and I could see that my insides did not match the textbook pictures. I have a spastic and tortuous (twisted) sigmoid colon. It looks like a ball of twisted snakes. Now they want a SITZ test to see how long it takes for markers to make it out of my system when I am not on laxatives….can anyone say forever? I am hoping that the problem can be surgically fixed and I may have some relief from this misery. Has anyone else had this problem?