pollution chimney-324561_640
Living With CFResearchRespiratory Disease

Respiratory Health and Pollution

The impact of small particle air pollution on the lower airways (lungs) has long been studied, but now scientists have evidence of its negative impact on the upper sinonasal airways as well. The World Health Organization’s recommendation for small particle air pollution (PM2.5) is that it not exceed an average …

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GeneticsLiving With CFRespiratory DiseaseTreatments

Does Ivacaftor Affect Lung Bacteria in Cystic Fibrosis?

Ivacaftor has been shown to increase CFTR activity and lung function in people with Cystic Fibrosis and the G551D mutation, but until a recent study, scientists were not sure if ivacaftor changed the level of bacteria in the lungs. The results of a deeper study on ivacaftor have been published, …

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Exercise
ExerciseLiving With CFResearchRespiratory Disease

Research on CF and Exercise

Significant research, both recent and decades old, shows that exercise helps people with CF. Yet it’s not always a part of a person’s treatment regimen. Here are some facts that may convince you to exercise more with the the guidance and approval of your CF team. “Exercise can provide improvements …

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Living With CFResearchRespiratory Disease

CF Lung Microbiome: Diversity and Lung Function

The article, The Lung Microbiome and Airway Disease, published September 2016 in the Annals of the American Thoracic Society, describes various research studies that analyzed the relationship between the lung microbiome and airway disease. Scientists can now better examine microbial communities in the lungs, and they are looking at how …

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Living With CFResearchRespiratory DiseaseTreatments

CFTR Function and Cigarette Smoke

Scientists are looking at how the CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) potentiator, Ivacaftor, might be used in COPD, specifically chronic bronchitis. They found that cigarette smoking reduces CFTR activity in lung tissue, and that exposing the lung cells directly to a CFTR potentiator reverses this effect. While the vast …

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photo of Staph bacteria from NIH (public domain)
Living With CFResearchRespiratory Disease

The Lung Microbiome and Dysbiosis

The “microbiome” is a hot topic in respiratory medicine, with researchers from diverse fields such as chronic obstructive pulmonary disease, bronchiectasis, pulmonary fibrosis, and lung transplantation seeking to use the newly accessible technology of bacterial ribosomal RNA sequencing and related technologies to characterize airway bacterial communities and to determine the …

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Living With CFResearchRespiratory DiseaseVideo

Webinar: Infection Prevention During Bronchoscopy

Laurence Muscarella Ph.D. and Atul Mehta M.D.   Webinar Highlights: The latest research into bronchoscope cross-contamination issues Most frequent causes of infection risks Most importantly:  what everyone who uses bronchoscope should kow to prevent risks Webinar

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Living With CFResearchRespiratory Disease

Copper in Hospitals to Limit Cross-Infection

Using copper on high-touch surfaces in hospitals may reduce Hospital-Acquired-Infections, according to a report published in the American Journal of Infection Control. The New York Times article describing this report says: …on average, fixtures in copper-equipped rooms had concentrations of bacteria about 98 percent lower than in rooms furnished with …

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Living With CFResearchRespiratory Disease

Distinguishing Relapse from Reinfection in MAC

In the News A study was published this month in the Annals of the American Thoracic Society (ATS) that looked at the differences between relapse of infection and a reinfection of the lungs by Mycobacterium avium complex (MAC). The study was not done with CF patients, however, the findings may …

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Living With CFRespiratory DiseaseTechnology

A New Tool for CF Lung Monitoring

Ultrashort Echo-Time MRI has been shown in a recent study, published last week in the Annals of the American Thoracic Society, to be comparable to computerized tomography (CT scanning) in measuring CF lung disease. This is excellent news as it offers a tool that is precise and detailed like CT, …

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